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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAPPA2
All Species:
4.55
Human Site:
S1250
Identified Species:
12.5
UniProt:
Q9BXP8
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BXP8
NP_064714.2
1791
198539
S1250
N
E
T
Q
D
D
R
S
E
Q
P
E
G
S
L
Chimpanzee
Pan troglodytes
XP_514020
1791
198653
S1250
N
E
T
Q
D
D
R
S
E
Q
P
E
G
S
L
Rhesus Macaque
Macaca mulatta
XP_001095160
1573
175281
P1082
K
D
C
G
V
Y
T
P
Q
G
F
L
D
Q
W
Dog
Lupus familis
XP_537179
1778
195855
E1241
R
L
Q
D
K
R
S
E
Q
T
E
G
S
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8R4K8
1624
181300
V1133
S
H
D
L
G
L
H
V
L
S
C
R
N
N
P
Rat
Rattus norvegicus
XP_001073420
1788
198541
R1250
K
K
D
Q
D
A
G
R
E
K
S
K
D
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_426627
1551
171156
Q1060
H
K
P
Q
V
T
I
Q
L
G
D
V
D
G
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_695417
1759
195473
V1243
D
Q
S
V
W
L
Q
V
G
F
E
R
P
G
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795597
1601
177169
P1110
F
D
F
D
Q
S
H
P
R
I
S
V
E
L
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
39.7
81.7
N.A.
43.6
79.4
N.A.
N.A.
57.9
N.A.
48
N.A.
N.A.
N.A.
N.A.
33.6
Protein Similarity:
100
99.7
56.3
89
N.A.
60
87.2
N.A.
N.A.
68.2
N.A.
63.8
N.A.
N.A.
N.A.
N.A.
49
P-Site Identity:
100
100
0
0
N.A.
0
33.3
N.A.
N.A.
13.3
N.A.
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
13.3
6.6
N.A.
13.3
53.3
N.A.
N.A.
26.6
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
12
0
0
0
0
0
0
0
12
0
0
0
0
% C
% Asp:
12
23
23
23
34
23
0
0
0
0
12
0
34
0
0
% D
% Glu:
0
23
0
0
0
0
0
12
34
0
23
23
12
0
12
% E
% Phe:
12
0
12
0
0
0
0
0
0
12
12
0
0
0
0
% F
% Gly:
0
0
0
12
12
0
12
0
12
23
0
12
23
23
0
% G
% His:
12
12
0
0
0
0
23
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
12
0
0
12
0
0
0
0
0
% I
% Lys:
23
23
0
0
12
0
0
0
0
12
0
12
0
0
0
% K
% Leu:
0
12
0
12
0
23
0
0
23
0
0
12
0
23
56
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
23
0
0
0
0
0
0
0
0
0
0
0
12
12
0
% N
% Pro:
0
0
12
0
0
0
0
23
0
0
23
0
12
0
12
% P
% Gln:
0
12
12
45
12
0
12
12
23
23
0
0
0
12
0
% Q
% Arg:
12
0
0
0
0
12
23
12
12
0
0
23
0
0
0
% R
% Ser:
12
0
12
0
0
12
12
23
0
12
23
0
12
34
0
% S
% Thr:
0
0
23
0
0
12
12
0
0
12
0
0
0
0
0
% T
% Val:
0
0
0
12
23
0
0
23
0
0
0
23
0
0
12
% V
% Trp:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
12
% W
% Tyr:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _